Search results: 15,076 results (approx.)

1. Heat-killed Lactobacillus reuteri GMNL-263 inhibits systemic lupus erythematosus-induced cardiomyopathy in NZB/W F1 mice.

It has been increasingly recognized that accelerated atherosclerosis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus, a multisystem autoimmune disease. In this study, we investigated the anti-apoptotic effects of heat-killed Lactobacillus reuteri GMNL-263...

Author(s) : Yeh YuLan; Lu MinChi; Tsai ChiKang [Tsai, C. K. B.]; Tzang BorShow; Cheng ShiuMin; Zhang XiaoYong; Yang LiangYo; Mahalakshmi, B.; Kuo WeiWen; Xiang Peng; Huang ChihYang

Publisher : Springer, New York, USA

Journal article : Probiotics and Antimicrobial Proteins 2021 Vol.13 No.1 pp.51-59 ref.36

2. Study on immunogenicity and antigenicity of a novel brucella multiepitope recombined protein.

Currently, brucellosis is a reemerged zoonotic infectious disease with an increased incidence in recent years. A simple, rapid and sensitive method for diagnosing brucellosis can help to reduce medical burden and economic loss. Previously, a multiple epitope recombinant protein was constructed...

Author(s) : Yin DeHui; Bai QiongQiong; Li Li; Xu Kun; Zhang JinPeng

Publisher : Elsevier, Amsterdam, Netherlands

Journal article : Biochemical and Biophysical Research Communications 2021 Vol.540 pp.37-41

3. Unexpected low expression of porcine endogenous retroviruses (PERVS) in porcine expanded potential stem cells (EPSCS).

Expanded potential stem cells (EPSCs) have been recently derived from porcine preimplantation embryos (Gao et al., 2019). These cells were shown to express key pluripotency genes, to be genetically stable and differentiate to derivatives of the three germ layers and additionally to trophoblast....

Author(s) : Krüger, L.; Nowak-Imialek, M.; Kristiansen, Y.; Herrmann, D.; Petersen, B.; Denner, J.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Virus Research 2021 Vol.294

4. Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026.

We report the generation of a full-length infectious cDNA clone for porcine deltacoronavirus strain USA/IL/2014/026. Similar to the parental strain, the infectious clone virus (icPDCoV) replicated efficiently in cell culture and caused mild clinical symptoms in piglets. To investigate putative...

Author(s) : Deng XuFang; Buckley, A. C.; Pillatzki, A.; Lager, K. M.; Baker, S. C.; Faaberg, K. S.

Publisher : Elsevier, Amsterdam, Netherlands

Journal article : Virology 2021 Vol.553 pp.35-45 ref.35

5. Isolation and identification of circovirus in pigeon.

The purpose of this study is first trial to detect of pigeon circovirus, so 1st group include 100 cloacal swabs were collected 55 healthy and 45 ill pigeons, 36 yearlings and 64 adults, the 2nd group included organs was liver, spleen, bursa of Fabricius from 41 young pigeons 10-30 days old and...

Author(s) : Al-Baroodi, S. Y.; Al-Attar, M. Y.

Publisher : College of Veterinary Medicine, University of Mosul, Mosul, Iraq

Journal article : Iraqi Journal of Veterinary Sciences 2021 Vol.35 No.1 pp.207-210 ref.18

6. Characterisation and bioactivities of an exopolysaccharide from an Antarctic bacterium Shewanella frigidimarina W32-2.

The continent of Antarctica breeds numerous special extremophiles that have adapted to the extreme variation of environment with a wide range of novel biodiversity. A cold-adapted bacterium Shewanella frigidimarina W32-2, isolated from Antarctic sediments, was identified to be a promising candidate ...

Author(s) : Chen YiMin; Gao PeiLi; Tang Xu; Xu ChangAn

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.530 ref.many

7. Research progress and prospects for the use of aptamers in aquaculture biosecurity.

The rapidly expanding scale of aquaculture has resulted in frequent pathogen outbreaks. Herein we review and discuss the application of aptamers in aquaculture biosecurity, including their use in the development of rapid diagnostic assays and effective therapeutic agents against aquaculture...

Author(s) : Yu Qing; Liu MingZhu; Wei ShiNa; Qin XianLing; Qin QiWei; Li PengFei

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.534

8. Method for specific identification of the emerging zoonotic pathogen Vibrio vulnificus lineage 3 (formerly biotype 3).

Vibrio vulnificus is a zoonotic pathogen that is spreading worldwide due to global warming. Lineage 3 (L3; formerly biotype 3) includes the strains of the species with the unique ability to cause fish farm-linked outbreaks of septicemia. The L3 strains emerged recently and are particularly virulent ...

Author(s) : Carmona-Salido, H.; Bisharat, N.; Amaro, C.

Publisher : American Society for Microbiology (ASM), Washington, D.C., USA

Journal article : Journal of Clinical Microbiology 2021 Vol.59 No.2

9. Assessment of the usefulness of anti-wb123 antibody for post-elimination surveillance of lymphatic filariasis.

The World Health Organization has targeted lymphatic filariasis (LF) for elimination as a public health problem and recommends, among other measures, post-elimination surveillance of LF. The identification of sensitive and specific surveillance tools is therefore a research priority. The Wuchereria ...

Author(s) : Dorkenoo, A. M.; Koba, A.; Halatoko, W. A.; Teko, M.; Kossi, K.; Yakpa, K.; Bronzan, R. N.

Publisher : BioMed Central Ltd, London, UK

Journal article : Parasites and Vectors 2021 Vol.14 No.23

10. A screening study of high affinity peptide as molecular binder for AXL, tyrosine kinase receptor involving in Zika virus entry.

The recent extensive spread of Zika virus has led to increased interest in the development of early diagnostic tests. To the best of our knowledge, this is the first study to demonstrate the successful use of phage display to identify affinity peptides for quantitative analysis of AXL, a tyrosine...

Author(s) : Kim JiHong; Koh ByumSeok; Ahn DaeGyun; Lee SeiJung; Park TaeJung; Park JongPil

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Bioelectrochemistry 2021 Vol.137 ref.19

11. PCR procedures to amplify GC-rich DNA sequences of Mycobacterium bovis.

Amplification of high GC content genes by PCR is a major challenge during the creation of recombinant GC-rich DNA constructs. This may be due to the difficulty in DNA denaturation or the possibility of forming secondary structures from DNA templates. Tools have been described to address the...

Author(s) : Assal, N.; Lin, M.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Microbiological Methods 2021 Vol.181 ref.13

12. Recent advances and challenges in microbial production of human milk oligosaccharides.

Human milk oligosaccharides (HMOs) are one of the major differences between livestock milk and human milk, and the prebiotic functions of HMOs have been verified through in vitro and clinical trials. The most abundant HMOs include 2'-fucysollactose (2'-FL), 3-fucosyllactose (3-FL), lacto-...

Author(s) : Deng JieYing; Lv XueQin; Li JiangHua; Du GuoCheng; Chen Jian; Liu Long

Publisher : Springer Nature Publishing AG, Cham, Switzerland

Journal article : Systems Microbiology and Biomanufacturing 2021 Vol.1 No.1 pp.1-14 ref.76

13. Cytokine biomarker discovery in the white rhinoceros (Ceratotherium simum).

Bovine tuberculosis (bTB), caused by Mycobacterium bovis (M. bovis) infection, disrupts conservation programs of threatened species such as the white rhinoceros (Ceratotherium simum). Interferon gamma release assays have been developed for the diagnosis of M. bovis infection in rhinoceros, however, ...

Author(s) : Chileshe, J.; Kerr, T. J.; Kinnear, C.; Buss, P. E.; Helden, P. D. van; Warren, R. M.; Miller, M. A.; Parsons, S. D. C.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Veterinary Immunology and Immunopathology 2021 Vol.232

14. Warp-speed COVID-19 vaccine development: beneficiaries of maturation in biopharmaceutical technologies and public-private partnerships.

It is anticipated that effective vaccines will enable the resumption of social and economic normalcy. Current calls for masking, social distancing and other restrictive measures for the public-good are difficult to enforce and are unstainable. As ~2-4% of the 50 million SARS-CoV2-infected have...

Author(s) : Ho, R. J. Y.

Publisher : Elsevier Inc., Philadelphia, USA

Journal article : Journal of Pharmaceutical Sciences 2021 Vol.110 No.2 pp.615-618 ref.8

15. Modulation by Anisakis simplex antigen of inflammatory response generated in experimental autoimmune encephalomyelitis.

The impact of immunization with Anisakis simplex larval antigen on the occurrence and progression of experimental autoimmune encephalomyelitis (EAE) induced in mice was studied. C57BL/6J mice were immunized with the MOG35-55 peptide and one batch was treated with A. simplex total larval antigen on...

Author(s) : Rodero, M.; Cuéllar, C.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : International Immunopharmacology 2021 Vol.90

16. Production of a full chimeric mouse x pig anti-porcine DEC205 receptor recombinant antibody.

Recombinant hybrid antibodies are commonly used in antigen-targeting assays to reduce the immunogenic potential associated with using classic mouse antibodies in other species. The DEC205 receptor has become an attractive target due to its effectiveness in activating the immune response and is...

Author(s) : Bustamante-Córdova, L.; Melgoza-González, E. A.; Parra-Sánchez, H.; Reséndiz-Sandoval, M.; Burgara-Estrella, A. J.; Hernández, J.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Journal of Immunological Methods 2021 Vol.489

17. Two immunogenic recombinant protein vaccine candidates showed disparate protective efficacy against Zika virus infection in rhesus macaques.

Zika virus (ZIKV) infection has caused major public health problems recently. To develop subunit vaccines for ZIKV, we have previously constructed recombinant ZIKV envelope protein domain III (EDIII), and the entire ectodomain (E80, which comprises EDI, EDII and EDIII), as vaccine candidates and...

Author(s) : Yang RuoHeng; Liu QingWei; Pang Wei; Gao Fei; Liang HuaBin; Zhang Wei; Lin YaLong; Li Min; Liu ZhiHua; Gao, G. F.; Zhang LinQi; Xiao Hui; Zheng YongTang; Huang Zhong; Jin Xia

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Vaccine 2021 Vol.39 No.6 pp.915-925

18. Generating aptamers for specific recognition against soft-shelled turtle iridovirus infection.

Soft-shelled turtle iridovirus (STIV) causes devastating virus disease in farmed soft-shelled turtles (Trionyx sinensis). Aptamers with remarkably high specificity and affinity have been widely applied in diseases diagnosis and therapies. In this study, single-stranded DNA (ssDNA) aptamers were...

Author(s) : Yu Qing; Liu MingZhu; Li MengMeng; Su MeiZhen; Xiao Rui; Tong GuiXiang; Qin XianLing; Li PengFei

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.535

19. Establishment of recombinase polymerase amplification technology for detecting Viral Hemorrhagic Septicemia Virus (VHSV) in cultured aquatic animals.

We established a recombinase polymerase amplification (RPA) assay for the rapid detection of viral hemorrhagic septicemia virus (VHSV) using primers designed to the N gene in this species. Optimization experiments showed that the optimal amplification temperature of the RPA assay was 37°C and that...

Author(s) : Weili Yin; Wei HuAng; Xiaojing Liu; Yangfan Ni; Bai Yang; Qing Shi; Weiduo Zhao; Tao Sun

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.535

20. Rescue of NanoLuc luciferase-expressing Senecavirus A with oncolytic activity.

Senecavirus A (SVA), previously known as Seneca Valley virus, is classified into the genus Senecavirus in the family Picornaviridae. SVA is not pathogenic to normal human cells, but has potent oncolytic activity in some tumor cells with neuroendocrine feature, such as small cell lung cancer (SCLC)...

Author(s) : Liu FuXiao; Wang QianQian; Huang YiLan; Wang Ning; Shan Hu

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Virus Research 2021 Vol.292

21. Ammonium produced from Shewanella strain 0409 contributes to antiviral activity against Betanodavirus.

Nervous necrosis virus (NNV) (genus: Betanodavirus) attacks aquacultured fish. Biocontrol may prevent and control the disease caused by NNV infection. Shewanella strain 0409 was isolated from the microbiome of grouper intestines, and its culture supernatant (CS0409) could inhibit NNV replication in ...

Author(s) : Wu YuChi; Tsai ChiaHong; Chi ShauChi

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.533

22. Synthesis and immunogenicity of Brucella monovalent neoglycoconjugate.

Brucellosis is a highly infectious zoonotic disease caused by Brucella. It is necessary to control and eliminate brucellosis. The cell wall O-polysaccharides of pathogenic Brucella species are homopolymers of the rare sugar 4,6-dideoxy-4-formamido-α-D-mannopyranose. Herein, one neoglycoconjugate...

Author(s) : Hao TianTian; Wang HaoMeng; Liu JiaCheng; Zhang Qian; Liu YuNing; Zhao LianBo; Zhu Tao; Yu Peng; Guo Na; Meng Xin

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Carbohydrate Research 2021 Vol.499

23. Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis.

In the present work we have focused on the Histone Deacetylase (HDAC) control of myeloid cells behavior during Xenopus tail regeneration. Here we show that myeloid differentiation is crucial to modulate the regenerative ability of Xenopus tadpoles in a HDAC activity-dependent fashion. HDAC activity ...

Author(s) : Pentagna, N.; Costa, T. P. da; Cardoso, F. S. dos S.; Almeida, F. M. de; Martinez, A. M. B.; Abreu, J. G.; Levin, M.; Carneiro, K.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Developmental and Comparative Immunology 2021 Vol.114 ref.many

24. Identification of specific serotypes of fowl adenoviruses isolated from diseased chickens by PCR.

We have developed a polymerase chain reaction (PCR) assay to facilitate detection of the major disease-associated serotypes of fowl adenovirus (FAdV) including serotypes 1, 2, 4, 8a and 8b; primers were designed based on serotype-specific sequences of the hexon gene. We tested field isolates from...

Author(s) : Mase, M.; Hiramatsu, K.; Nishijima, N.; Iseki, H.; Watanabe, S.

Publisher : Japanese Society of Veterinary Science, Tokyo, Japan

Journal article : Journal of Veterinary Medical Science 2021 Vol.83 No.1 pp.130-133 ref.20

25. Efficacy of a Turkey herpesvirus vectored Newcastle disease vaccine against genotype VII.1.1 virus: challenge route affects shedding pattern.

The control of Newcastle disease (ND) highly relies on vaccination. Immunity provided by a ND vaccine can be characterized by measuring the level of clinical protection and reduction in challenge virus shedding. The extent of shedding depends a lot on the characteristics of vaccine used and the...

Author(s) : Palya, V.; Tatár-Kis, T.; Arafa, A. S. A.; Felföldi, B.; Mató, T.; Setta, A.

Publisher : MDPI AG, Basel, Switzerland

Journal article : Vaccines 2021 Vol.9 No.1 ref.36


Warp-speed COVID-19 vaccine development: beneficiaries of maturation in biopharmaceutical technologies and public-private partnerships. It is anticipated that effective vaccines will enable the resumption of social and economic normalcy. Current calls for masking, social distancing and other restrictive measures for the public-good are difficult to enforce and are unstainable. As ~2-4% of the 50 million SARS-CoV2-infected have...

Author(s) : Ho, R. J. Y.

Publisher : Elsevier Inc., Philadelphia, USA

Journal article : Journal of Pharmaceutical Sciences 2021 Vol.110 No.2 pp.615-618 ref.8

15. Modulation by Anisakis simplex antigen of inflammatory response generated in experimental autoimmune encephalomyelitis.

The impact of immunization with Anisakis simplex larval antigen on the occurrence and progression of experimental autoimmune encephalomyelitis (EAE) induced in mice was studied. C57BL/6J mice were immunized with the MOG35-55 peptide and one batch was treated with A. simplex total larval antigen on...

Author(s) : Rodero, M.; Cuéllar, C.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : International Immunopharmacology 2021 Vol.90

16. Production of a full chimeric mouse x pig anti-porcine DEC205 receptor recombinant antibody.

Recombinant hybrid antibodies are commonly used in antigen-targeting assays to reduce the immunogenic potential associated with using classic mouse antibodies in other species. The DEC205 receptor has become an attractive target due to its effectiveness in activating the immune response and is...

Author(s) : Bustamante-Córdova, L.; Melgoza-González, E. A.; Parra-Sánchez, H.; Reséndiz-Sandoval, M.; Burgara-Estrella, A. J.; Hernández, J.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Journal of Immunological Methods 2021 Vol.489

17. Two immunogenic recombinant protein vaccine candidates showed disparate protective efficacy against Zika virus infection in rhesus macaques.

Zika virus (ZIKV) infection has caused major public health problems recently. To develop subunit vaccines for ZIKV, we have previously constructed recombinant ZIKV envelope protein domain III (EDIII), and the entire ectodomain (E80, which comprises EDI, EDII and EDIII), as vaccine candidates and...

Author(s) : Yang RuoHeng; Liu QingWei; Pang Wei; Gao Fei; Liang HuaBin; Zhang Wei; Lin YaLong; Li Min; Liu ZhiHua; Gao, G. F.; Zhang LinQi; Xiao Hui; Zheng YongTang; Huang Zhong; Jin Xia

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Vaccine 2021 Vol.39 No.6 pp.915-925

18. Generating aptamers for specific recognition against soft-shelled turtle iridovirus infection.

Soft-shelled turtle iridovirus (STIV) causes devastating virus disease in farmed soft-shelled turtles (Trionyx sinensis). Aptamers with remarkably high specificity and affinity have been widely applied in diseases diagnosis and therapies. In this study, single-stranded DNA (ssDNA) aptamers were...

Author(s) : Yu Qing; Liu MingZhu; Li MengMeng; Su MeiZhen; Xiao Rui; Tong GuiXiang; Qin XianLing; Li PengFei

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.535

19. Establishment of recombinase polymerase amplification technology for detecting Viral Hemorrhagic Septicemia Virus (VHSV) in cultured aquatic animals.

We established a recombinase polymerase amplification (RPA) assay for the rapid detection of viral hemorrhagic septicemia virus (VHSV) using primers designed to the N gene in this species. Optimization experiments showed that the optimal amplification temperature of the RPA assay was 37°C and that...

Author(s) : Weili Yin; Wei HuAng; Xiaojing Liu; Yangfan Ni; Bai Yang; Qing Shi; Weiduo Zhao; Tao Sun

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.535

20. Rescue of NanoLuc luciferase-expressing Senecavirus A with oncolytic activity.

Senecavirus A (SVA), previously known as Seneca Valley virus, is classified into the genus Senecavirus in the family Picornaviridae. SVA is not pathogenic to normal human cells, but has potent oncolytic activity in some tumor cells with neuroendocrine feature, such as small cell lung cancer (SCLC)...

Author(s) : Liu FuXiao; Wang QianQian; Huang YiLan; Wang Ning; Shan Hu

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Virus Research 2021 Vol.292

21. Ammonium produced from Shewanella strain 0409 contributes to antiviral activity against Betanodavirus.

Nervous necrosis virus (NNV) (genus: Betanodavirus) attacks aquacultured fish. Biocontrol may prevent and control the disease caused by NNV infection. Shewanella strain 0409 was isolated from the microbiome of grouper intestines, and its culture supernatant (CS0409) could inhibit NNV replication in ...

Author(s) : Wu YuChi; Tsai ChiaHong; Chi ShauChi

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Aquaculture 2021 Vol.533

22. Synthesis and immunogenicity of Brucella monovalent neoglycoconjugate.

Brucellosis is a highly infectious zoonotic disease caused by Brucella. It is necessary to control and eliminate brucellosis. The cell wall O-polysaccharides of pathogenic Brucella species are homopolymers of the rare sugar 4,6-dideoxy-4-formamido-α-D-mannopyranose. Herein, one neoglycoconjugate...

Author(s) : Hao TianTian; Wang HaoMeng; Liu JiaCheng; Zhang Qian; Liu YuNing; Zhao LianBo; Zhu Tao; Yu Peng; Guo Na; Meng Xin

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Carbohydrate Research 2021 Vol.499

23. Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis.

In the present work we have focused on the Histone Deacetylase (HDAC) control of myeloid cells behavior during Xenopus tail regeneration. Here we show that myeloid differentiation is crucial to modulate the regenerative ability of Xenopus tadpoles in a HDAC activity-dependent fashion. HDAC activity ...

Author(s) : Pentagna, N.; Costa, T. P. da; Cardoso, F. S. dos S.; Almeida, F. M. de; Martinez, A. M. B.; Abreu, J. G.; Levin, M.; Carneiro, K.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Developmental and Comparative Immunology 2021 Vol.114 ref.many

24. Identification of specific serotypes of fowl adenoviruses isolated from diseased chickens by PCR.

We have developed a polymerase chain reaction (PCR) assay to facilitate detection of the major disease-associated serotypes of fowl adenovirus (FAdV) including serotypes 1, 2, 4, 8a and 8b; primers were designed based on serotype-specific sequences of the hexon gene. We tested field isolates from...

Author(s) : Mase, M.; Hiramatsu, K.; Nishijima, N.; Iseki, H.; Watanabe, S.

Publisher : Japanese Society of Veterinary Science, Tokyo, Japan

Journal article : Journal of Veterinary Medical Science 2021 Vol.83 No.1 pp.130-133 ref.20

25. Efficacy of a Turkey herpesvirus vectored Newcastle disease vaccine against genotype VII.1.1 virus: challenge route affects shedding pattern.

The control of Newcastle disease (ND) highly relies on vaccination. Immunity provided by a ND vaccine can be characterized by measuring the level of clinical protection and reduction in challenge virus shedding. The extent of shedding depends a lot on the characteristics of vaccine used and the...

Author(s) : Palya, V.; Tatár-Kis, T.; Arafa, A. S. A.; Felföldi, B.; Mató, T.; Setta, A.

Publisher : MDPI AG, Basel, Switzerland

Journal article : Vaccines 2021 Vol.9 No.1 ref.36