Search results: 78,768 results (approx.)

1. Dynamical network biomarkers: theory and applications.

This paper reviews theory of DNB (Dynamical Network Biomarkers) and its applications including both modern medicine and traditional medicine. We show that omics data such as gene/protein expression profiles can be effectively used to detect pre-disease states before critical transitions from...

Author(s) : Aihara, K.; Liu Rui; Koizumi, K.; Liu XiaoPing; Chen LuoNan

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Gene 2022 Vol.808 ref.47

2. Pharmacokinetic study of clarithromycin in human breast milk by UPLC-MS/MS.

This study aimed to develop a validated UPLC-MS/MS method for pharmacokinetic analysis of clarithromycin in human breast milk. For sample preparation, proteins precipitated with methanol and azithromycin were used as internal standards. Clarithromycin and azithromycin detection was achieved using...

Author(s) : Kul, A.; Ozdemir, M.; Sagirli, O.

Publisher : Elsevier B.V., Amsterdam, Netherlands

Journal article : Journal of Pharmaceutical and Biomedical Analysis 2022 Vol.208 ref.35

3. Quercetin mitigates oxidative stress, developmental toxicity and teratogenic effects induced by high-dose vitamin D2 in zebrafish embryos.

The aim of the study was to determine the developmental toxicity of high-dose administration of vitamin D2 (vit. D2) and the synergistic effect of vit. D2 in co-treatment with quercetin. Zebrafish embryos at 6 hpf were treated with either vit. D2 (1, 5, 10 μg/mL) or quercetin (5, 10 μg/mL) alone....

Author(s) : Chang SukkumNgullie; Kim HyunJin; Kang SunChul

Publisher : Central Fisheries Research Institute (CFRI), Trabzon, Turkey

Journal article : Turkish Journal of Fisheries and Aquatic Sciences 2022 Vol.22 No.3

4. Development of a rapid UPLC-MS/MS method for the determination of toddalolactone in mouse blood and its application in pharmacokinetics.

A rapid and simple UPLC-MS/MS method was developed to determine toddalolactone in mouse blood and applied to measure the pharmacokinetics of toddalolactone in mice. Blood samples were first preprocessed by ethyl acetate liquid-liquid extraction. Oxypeucedanin hydrate (internal standard, IS) and...

Author(s) : Zhou Jing; Wang HongZhe; Miao CaiYun; Yao YunXi; Ma JianShe

Publisher : Akadémiai Kiadó, Budapest, Hungary

Journal article : Acta Chromatographica 2022 Vol.34 No.1 pp.18-23 ref.17

5. Potential nephroprotective phytochemicals: mechanism and future prospects.

Ethnopharmacological relevance: Kidney disease (KD) is one of the serious health issues, which causes worrisome morbidity and economic burden. Therapeutic strategies are available however majority of them are associated with severe adverse effects and poor patient compliance and adherence. This...

Author(s) : Parakh Basist; Bushra Parveen; Sultan Zahiruddin; Gaurav Gautam; Rabea Parveen; Khan, M. A.; Anuja Krishnan; Mohd Shahid; Sayeed Ahmad

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.283 ref.237

6. Ethnodermatological use of medicinal plants in India: from ayurvedic formulations to clinical perspectives - a review.

Ethnopharmacological relevance: Traditional knowledge is a particular form of practice or skill set that was developed in ancient times and was sustained through generations via the passing of knowledge, essentially confined within a specific tribe, local people, or family lineages....

Author(s) : Uttpal Anand; Tudu, C. K.; Samapika Nandy; Kumari Sunita; Vijay Tripathi; Loake, G. J.; Abhijit Dey; Procków, J.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284 ref.many

7. Catharanthus roseus (L.) G. Don: a review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities.

Ethnopharmacological relevance: Catharanthus roseus (L.) G. Don is a well known medicinal plant belonging to family Apocynaceae that have been traditionally used as medicine since ancient times. C. roseus is a well-recognized herbal medicine due to its anticancer bisindole alkaloids (vinblastine...

Author(s) : Sunil Kumar; Bikarma Singh; Ramesh Singh

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284

8. A comprehensive review of ethnopharmacology, phytochemistry, pharmacology, and pharmacokinetics of Schisandra chinensis (Turcz.) Baill. and Schisandra sphenanthera Rehd. et Wils.

Ethnopharmacological relevance: Schisandra chinensis (called bei-wuweizi in Chinese, S. chinensis) and Schisandra sphenanthera (called nan-wuweizi in Chinese, S. sphenanthera) are two highly similar plants in the Magnoliaceae family. Their dried ripe fruits are commonly used as traditional Chinese...

Author(s) : Yang Ke; Qiu Jing; Huang ZeCheng; Yu ZiWei; Wang WenJun; Hu HuiLing; You Yu

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284

9. Traditional medicinal uses, pharmacology, phytochemistry, and distribution of the genus Fagaropsis (Rutaceae).

Ethnopharmacological relevance: Genus Fagaropsis belonging to the Rutaceae family, is widely distributed in Africa. The various parts of the species in this genus are used in traditional herbal medicine in different parts of the continent for the treatment of malaria, intestinal disorders, cancer,...

Author(s) : Mutinda, E. S.; Mkala, E. M.; Nanjala, C.; Waswa, E. N.; Odago, W. O.; Kimutai, F.; Tian, J.; Gichua, M. K.; Gituru, R. W.; Hu GuangWan

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284

10. Comparison of medicinal preparations of Ayurveda in India and five traditional medicines in China.

Ethnopharmacological relevance: Ayurveda is the main traditional healthcare system in Indian medicine. Tibetan medicine (TM), Mongolian medicine (MM), Buddhist medicine (BM), Dai medicine (DM), and Uyghur medicine (UM) are main traditional medicines practiced in China. These are existing...

Author(s) : Li XiaoLi; Wu Lei; Wu RuiXia; Sun Ming; Fu Ke; Kuang TingTing; Wang Zhang

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284

11. Dysphania schraderiana (Schult.) Mosyakin & Clemants - an overlooked medicinal and ritual plant used in Poland.

Ethnopharmacological relevance: The paper discusses the traditional ritual, medicinal and insect repellent use of Dysphania schraderiana in Poland, a plant with little ethnobotanical and phytochemical data. Our research suggests that its properties should be further studied comparing it with the...

Author(s) : Luczaj, L.; Wolanin, M.; Drobnik, J.; Kujawska, M.; Dumanowski, J.; Walker, K.; Tomczyk, M.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284 ref.many

12. China amyotrophic lateral sclerosis registry of patients with Traditional Chinese Medicine (CARE-TCM): rationale and design.

Ethnopharmacological relevance: Traditional Chinese medicine (TCM) has become popular interventional treatment for amyotrophic lateral sclerosis (ALS). However, lack of knowledge about the general characteristics and long-term clinical outcomes hampers the development of herbal drugs for ALS. Aim...

Author(s) : Song YueBo; Li MingXuan; Sugimoto, K.; Han Yi; Liu Jia; Ma Bin; Song HuJie; Zhang Chi; Gao Ying

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2022 Vol.284

13. Chronic consumption of a high linoleic acid diet during pregnancy, lactation and post-weaning period increases depression-like behavior in male, but not female offspring.

Polyunsaturated fatty acids (PUFAs) play an essential role in brain development. Emerging data have suggested a possible link between an imbalance in PUFAs and cognitive behavioral deficits in offspring. A diet rich in high linoleic acid (HLA), typically from preconception to lactation, leads to an ...

Author(s) : Yau SukYu; Yip SiuLing [Yip, S. L. Y.]; Formolo, D. A.; He Siyuen; Lee HoYin [Lee, H. Y. T.]; Wen ChunYi; Hryciw, D. H.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Behavioural Brain Research 2022 Vol.416 ref.96

14. 1,8-cineole: a review of source, biological activities, and application.

1,8-Cineole (also known as eucalyptol) is mostly extracted from the essential oils of plants, which showed extensively pharmacological properties including anti-inflammatory and antioxidant mainly via the regulation on NF-κB and Nrf2, and was used for the treatment of respiratory diseases and...

Author(s) : Cai ZiMin; Peng JianQing; Chen Yi; Tao Ling; Zhang YanYan; Fu LingYun; Long QingDe; Shen XiangChun

Publisher : Taylor & Francis, Abingdon, UK

Journal article : Journal of Asian Natural Products Research 2021 Vol.23 No.10 pp.938-954 ref.130

15. Lichens in folklore: medicine and dyes.

Lichens were mentioned in folklore of different cultures around the world for its ability to treat several diseases; thus, it has been used in folk medicine. Lichens were believed to be useful in the treatment of wounds, skin diseases, gastrointestinal and respiratory problems. It has been reported ...

Author(s) : Abdel-Fatta, A. F.

Publisher : Arab Society for Fungal Conservation, Ismailia, Egypt

Journal article : Microbial Biosystems 2021 Vol.5 No.1 pp.50-51

16. Pyriproxyfen does not cause microcephaly or malformations in a preclinical mammalian model.

Pyriproxyfen is used in Brazil to combat epidemics of Dengue Fever, Chikungunya Fever, and Zika virus. This study assessed the effects of pyriproxyfen on reproductive performance, embryo-fetal development, head measurements, and DNA integrity in a preclinical model. Thirty pregnant mice were...

Author(s) : Vani, J. M.; Schweich-Adami, L. de C.; Auharek, S. A.; Antoniolli-Silva, A. C. M. B.; Oliveira, R. J.

Publisher : Springer Berlin, Heidelberg, Germany

Journal article : Environmental Science and Pollution Research 2021 Vol.28 No.4 pp.4585-4593 ref.many

17. Synthesis of novel isoflavone/benzo-δ-sultam hybrids as potential anti-inflammatory drugs.

A small series of novel isoflavone/benzo-δ-sultam hybrids was synthesised and evaluated as potential anti-inflammatory and neuroprotective drugs in LPS-activated BV2 microglia. The benzo-δ-sultam core was constructed in a two-step reaction by coupling 2-halobenzenesulfonamide derivatives with...

Author(s) : Mengheres, G.; Rice, C. R.; Olajide, O. A.; Hemming, K.

Publisher : Elsevier, Cambridge, UK

Journal article : Bioorganic & Medicinal Chemistry Letters 2021 Vol.34

18. Research progress on quality evaluation methods of Xiaoyaosan preparations.

Xiaoyaosan, a classical prescription originated from Taiping Huimin Heji Jufang, has a wide range of clinical applications. At present, a variety of prescriptions of Xiaoyaosan have been put on the market. The quality research of Xiaoyao prescriptions which have been listed in recent years was...

Author(s) : Xu ShaoHua; Gong WenXia; Qin XueMei

Publisher : Drug Evaluation Research, Tianjin, China

Journal article : Drug Evaluation Research 2021 Vol.44 No.4 pp.885-893 ref.51

19. Regulatory and intellectual property conundrums surrounding xenotransplantation.

Author(s) : Kwisda, K.; Cantz, T.; Hoppe, N.

Publisher : Nature Publishing Group, New York, USA

Journal article : Nature Biotechnology 2021 Vol.39 No.7 pp.796-798 ref.23

20. Pharmacological strategies to prevent SARS-CoV-2 infection and treat the early phases of COVID-19.

A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the cause of coronavirus disease 2019 (COVID-19). It emerged in China in 2019 and has since spread worldwide. COVID-19 has a wide spectrum of clinical scenarios, ranging from totally asymptomatic to death....

Author(s) : Scarabel, L.; Guardascione, M.; Bo, M. D.; Toffoli, G.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : International Journal of Infectious Diseases 2021 Vol.104 pp.441-451 ref.many

21. Legislation and current developments in adverse drug reaction reporting in Mongolia: how far are we?

Monitoring adverse drug reactions is a vital issue to ensure drug safety and to protect the general public from medication-related harmful effects. In order to properly monitor drug safety, a regulatory system needs to be in place as well as an infrastructure that allows for analyzing national and...

Author(s) : Zulzaga, Z.; Myagmarsuren, E.; Woerdenbag, H. J.; Puijenbroek, E. P. van

Publisher : BioMed Central Ltd, London, UK

Journal article : Journal of Pharmaceutical Policy and Practice 2021 Vol.14 No.15 pp.(08 March 2021) ref.40

22. Barth syndrome: cardiolipin, cellular pathophysiology, management, and novel therapeutic targets.

Barth syndrome is a rare X-linked genetic disease classically characterized by cardiomyopathy, skeletal myopathy, growth retardation, neutropenia, and 3-methylglutaconic aciduria. It is caused by mutations in the tafazzin gene localized to chromosome Xq28.12. Mutations in tafazzin may result in...

Author(s) : Zegallai, H. M.; Hatch, G. M.

Publisher : Springer, New York, USA

Journal article : Molecular and Cellular Biochemistry 2021 Vol.476 No.3 pp.1605-1629 ref.194

23. Relationship between the use of Chinese herbal medicines and Sjögren syndrome risk among women with menopause: a retrospective cohort study.

Objective: Menopausal women appear to report a higher risk of Sjögren syndrome (SS). Although Chinese herbal medicines (CHMs) are proven to lower SS risk, the scientific evidence of whether it can lessen the occurrence of SS among menopausal women is limited. This longitudinal cohort study aimed to ...

Author(s) : Chung YuJung; Wei ChangKuo; Livneh, H.; Lai NingSheng; Lu MingChi; Liao HouHsun; Tsai TzungYi

Publisher : Lippincott Williams & Wilkins, Inc., Hagerstown, USA

Journal article : Menopause 2021 Vol.28 No.1 pp.58-64

24. Limonoids as an effective anticancer agent: a review.

Citrus limonoids (CLs) are a group of highly oxygenated terpenoid found mostly in the seeds, fruits and peel tissues of citrus fruits such as lemons, limes, pumellos, oranges, grapefruits, bergamots, and mandarins. [10] The term limonoids was derived from limonin, which is the first...

Author(s) : Mankar, N. O.; Mandlik, Y. R.; Chauriya, C. B.

Publisher : A and V Publications, Raipur, India

Journal article : Research Journal of Pharmaceutical Dosage Forms and Technology 2021 Vol.13 No.2 pp.118-120 ref.15

25. An overview of the mechanisms of marine fungi-derived anti-inflammatory and anti-tumor agents and their novel role in drug targeting.

Marine fungi with their successful pharmacological effects were considered to be the treasure of ocean medicines concerning the striking ability of their secondary metabolites. Literature over literature has been published on fungi derived bioactive molecules to probe its therapeutic potential....

Author(s) : Syed Shams-Ul-Hassan; Ishaq, M.; Zhang WeiDong; Jin HuiZi

Publisher : Bentham Science Publishers, Sharjah, United Arab Emirates

Journal article : Current Pharmaceutical Design 2021 Vol.27 No.22 pp.2605-2614 ref.56