Search results: 8,846 results (approx.)

1. A traditional herbal formula composed of 'white' herbs down regulates tyrosinase-related proteins in B16F10 melanoma cells.

The traditional Chinese medicine (TCM) theory postulates the pharmacological targets of white-coloured herbs include skin. To explore the therapeutic implications of this theory in skin disorders, especially for excess pigmentation, a series of anti-melanogenic evaluations were performed using a...

Author(s) : Bang ChaeYoung; Kim MinKyoung; Kim SuHyun; Kim DongIl; Choung SeYoung; Jang YoungPyo

Publisher : National Institute of Science Communication and Information Resources, CSIR, New Delhi, India

Journal article : Indian Journal of Traditional Knowledge 2017 Vol.16 No.1 pp.68-72 ref.23

2. Curative remedies for rheumatoid arthritis: herbal informatics approach for rational based selection of natural plant products.

Rheumatoid arthritis is a chronic inflammatory and systemic autoimmune disease characterized by joint pain, swelling and stiffness. Inflammatory mediators such as pro-inflammatory cytokines, IL-6, COX-2, TNF-alpha, etc. attack joints upon activation and generate reactive oxygen/nitrogen species,...

Author(s) : Ankit Tanwar; Pallavi Thakur; Raman Chawla; Ansari, M. M.; Chakotiya, A. S.; Siddharth Gusain; Rajeev Goel; Rajesh Arora; Sharma, R. K.; Khan, H. A.

Publisher : National Institute of Science Communication and Information Resources, CSIR, New Delhi, India

Journal article : Indian Journal of Traditional Knowledge 2017 Vol.16 No.1 pp.128-133 ref.22

3. Some pharmacological effects of Tityus obscurus venom in rats and mice.

There are a great number of studies about Brazilian scorpions. However, little is known about the venom of scorpions of northern Brazil, mainly about Tityus obscurus, which is responsible for the most number of accidents in the Amazon. Thus, this study aimed to evaluate some pharmacological effects ...

Author(s) : Santos-da-Silva, A. de P.; Candido, D. M.; Nencioni, A. L. A.; Kimura, L. F.; Prezotto Neto, J. P.; Barbaro, K. C.; Chalkidis, H. M.; Dorce, V. A. C.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Toxicon 2017 Vol.126 pp.51-58 ref.many

4. Tris (1, 3-dichloro-2-propyl) phosphate induces apoptosis and autophagy in SH-SY5Y cells: involvement of ROS-mediated AMPK/mTOR/ULK1 pathways.

Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP), an extensively used organophosphorus flame retardant, is frequently detected in the environment and biota. Recent studies have shown that TDCIPP has neurotoxic effects. We hypothesized that the neurotoxicity might occur via the induction of the...

Author(s) : Li RuiWen; Zhou PeiJiang; Guo YongYong; Lee JaeSeong; Zhou BingSheng

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Food and Chemical Toxicology 2017 Vol.100 pp.183-196 ref.many

6. Biosynthesis and therapeutic implications of iridoid glycosides from Picrorhiza genus: the road ahead.

Picrorhiza genus is emerging as an important paradigm for herbal drug formulations due to its versatile iridoid glycosides exhibition and robustness in the treatment of diverse infections including hepatic amoebiasis, cancer, malaria, ulcerative colitis and cerebral ischemia reperfusion injury....

Author(s) : Varun Kumar; Chauhan, R. S.; Chanderdeep Tandon

Publisher : Springer, New Delhi, India

Journal article : Journal of Plant Biochemistry and Biotechnology 2017 Vol.26 No.1 pp.1-13 ref.86

7. Effects of Ginkgo biloba on dementia: an overview of systematic reviews.

Objective: To assess the cumulative evidence on the efficacy and effectiveness of Ginkgo biloba extract (GbE) in the treatment of dementia. Design: Overview of systematic reviews. Methods: PubMed/MEDLINE, EMBASE, Cochrane, and Google Scholar were searched in June 2016. Systematic reviews (SRs) of...

Author(s) : Yuan QiuJu; Wang ChongWen; Shi Jun; Lin ZhiXiu

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.195 pp.1-9 ref.many

8. Ethnobotanical and phytopharmacological review of Scindapsus officinalis ("Gajapippali").

Scindapsus officinalis (S. officinalis) holds a reputed position in Ayurvedic system of medicine. It has been ethanobotanically used to treat diarrhea ("atisara"), worm infestation ("krmiroga"), and as antipyretic. Literature survey on S. officinalis was carried out via electronic search in PubMed, ...

Author(s) : Kuljeet Kaur; Rajiv Gupta

Publisher : Elsevier (Singapore) Pte Ltd, Hong Kong, China

Journal article : Asian Pacific Journal of Tropical Biomedicine 2017 Vol.7 No.1 pp.78-85 ref.130

9. An ex vivo evaluation of the efficacy of andrographolide in modulating differential expression of transcription factors and target genes in periodontal cells and its potential role in treating periodontal diseases.

Ethanopharmacological relevance: Andrographolide is a herbal extract traditionally used in South Asian countries for treating inflammatory diseases. Aim of the study: To evaluate the efficacy of andrographolide in management of periodontal disease which is a highly prevalent oral disease. Materials ...

Author(s) : Ambili, R.; Prasanthila Janam; Babu, P. S. S.; Manu Prasad; Vinod, D.; Kumar, P. R. A.; Kumary, T. V.; Nair, S. A.; Pillai, M. R.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.196 pp.160-167

10. Effect of St. John's wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report.

Ethnopharmacological relevance: Topical formulations such as oily extracts or ointments prepared with the flowering aerial parts of St. John's wort (Hypericum perforatum L., Hypericaceae) have been used in the management of a wide range dermatological problems including superficial wounds and...

Author(s) : Yücel, A.; Kan, Y.; Yesİlada, E.; Akın, O.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.196 pp.236-241

11. Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment.

Ethnopharmacological relevance: Alzheimer's disease (AD), as the most common type of dementia, has brought a heavy economic burden to healthcare system around the world. However, currently there is still lack of effective treatment for AD patients. Herbal medicines, featured as multiple herbs,...

Author(s) : Fang JianSong; Wang Ling; Wu Tian; Yang Cong; Gao Li; Cai HaoBin; Liu JunHui; Fang ShuHuan; Chen YunBo; Tan Wen; Wang Qi

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.196 pp.281-292

12. Effects of aqueous extracts of Ecliptae herba, Polygoni multiflori radix praeparata and Rehmanniae radix praeparata on melanogenesis and the migration of human melanocytes.

Ethnopharmacological relevance: Polygoni multiflori radix praeparata (PMRP), Ecliptae herba (EH) and Rehmanniae radix praeparata (RRP) are the most frequently-used herbs by Traditional Chinese Medicine practitioners for the treatment of vitiligo. Their abilities to stimulate melanogenesis,...

Author(s) : Xu Ping; Su ShuLan; Tan Cheng; Lai RenSheng; Min ZhongSheng

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.195 pp.89-95 ref.27

13. Antianxiety activity guided isolation and characterization of bergenin from Caesalpinia digyna Rottler roots.

Ethnopharmacological relevance: Caesalpinia digyna Rottler (Caesalpiniaceae) roots have been used traditionally for soothing nerves, as nervine tonic and febrifuge. The aim of the present study was to isolate the antianxiety constituent(s) from C. digyna roots following bioactivity guided...

Author(s) : Jitender Singh; Ashwani Kumar; Anupam Sharma

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2017 Vol.195 pp.182-187 ref.34

14. Clinical pharmacology of Citrus bergamia: a systematic review.

Citrus bergamia Risso et Poiteau ("Bergamot") originated from the Mediterranean ecoregion (southern Italy, Calabria). Bergamot essential oil (BEO) is used in perfumes, cosmetics, and for stress reduction. Juice from C. bergamia has been used for hyperlipidemia. We evaluated literature published on ...

Author(s) : Mannucci, C.; Navarra, M.; Calapai, F.; Squeri, R.; Gangemi, S.; Calapai, G.

Publisher : Wiley, Chichester, UK

Journal article : Phytotherapy Research 2017 Vol.31 No.1 pp.27-39 ref.47

15. Characterization of ion channels on subesophageal ganglion neurons from Chinese tarantula Ornithoctonus huwena: exploring the myth of the spider insensitive to its venom.

Chinese tarantula Ornithoctonus huwena is one of the most venomous spiders distributing in the hilly areas of southern China. In this study, using whole-cell patch-clamp technique we investigated electrophysiological and pharmacological properties of ion channels from tarantula subesophageal...

Author(s) : Deng MeiChun; Hu ZhaoTun; Cai TianFu; Liu Kai; Wu WenFang; Luo Xuan; Jiang LiPing; Wang MeiChi; Yang Jing; Xiao YuCheng; Liang SongPing

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Toxicon 2016 Vol.120 pp.61-68 ref.28

16. Description of Loxtox protein family and identification of a new group of Phospholipases D from Loxosceles similis venom gland.

Envenoming resulting from Loxosceles spider bites (loxoscelism) is a recognized public health problem in Brazil. However, the pathophysiology of loxoscelism caused by L. similis bites, which is widespread in Brazil, remains poorly understood. In the present work, the RNA sequencing (RNA-Seq - Next...

Author(s) : Dantas, A. E.; Carmo, A. O.; Horta, C. C. R.; Leal, H. G.; Oliveira-Mendes, B. B. R.; Martins, A. P. V.; Chávez-Olórtegui, C.; Kalapothakis, E.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Toxicon 2016 Vol.120 pp.97-106 ref.many

17. Untargeted MS-based small metabolite identification from the plant leaves and stems of Impatiens balsamina.

The identification of plant metabolites is very important for the understanding of plant physiology including plant growth, development and defense mechanism, particularly for herbal medicinal plants. The metabolite profile could possibly be used for future drug discovery since the pharmacological...

Author(s) : Chua LeeSuan

Publisher : Elsevier Masson, Paris, France

Journal article : Plant Physiology and Biochemistry 2016 Vol.106 pp.16-22 ref.48

18. Medicinal plant transcriptomes: the new gateways for accelerated understanding of plant secondary metabolism.

Medicinal plants are the vital source of numerous structurally diverse pharmacologically active metabolites collectively called as secondary metabolites finding extensive applications in traditional systems of medicine and in pharmaceutical industries. Several distinctive and complex pathways...

Author(s) : Sandhya Tripathi; Jadaun, J. S.; Muktesh Chandra; Sangwan, N. S.

Publisher : Cambridge University Press, Cambridge, UK

Journal article : Plant Genetic Resources: Characterization and Utilization 2016 Vol.14 No.4 pp.256-269 ref.96

19. Comparative powder microscopic and HPTLC studies on stem barks of Symplocos racemosa Roxb. and Symplocos crataegoides Ham.

Introduction: Comparative powder microscopic and HPTLC studies were carried out on stem barks of Symplocos racemosa Roxb. and Symplocos crataegoides Ham. to differentiate its identity in Ayurvedic formulations. Method: Powder microscopic and HPTLC studies of these barks were undertaken on a...

Author(s) : Nartunai Govindarajan; Cheekala, U. M. R.; Shantha Arcot; Susikumar Sundaramoorthy; Murugammal Shanmugam; Ramasamy Duraisamy; Cheemalapati, V. N.; Ilavarasan Raju

Publisher : Phcog.Net, Bangalore, India

Journal article : Pharmacognosy Journal 2016 Vol.8 No.4 pp.346-351 ref.14

20. Chemical and medico biological applications of the genus Costus (Gingers).

Many herbal remedies individually or in combination have been recommended in various medical treatises for the cure of different diseases. Medicinal plants have served as nature's gift to make disease free healthy life. The genus Costus Linn. Belongs to family Costaceae, which has been separated...

Author(s) : Anusha Ajayakumar; Sini, K. R.; Sreekanth, M. C.

Publisher : Journal of Chemical and Pharmaceutical Research, Jaipur, India

Journal article : Journal of Chemical and Pharmaceutical Research 2016 Vol.8 No.8 pp.453-458 ref.73

21. Chemical constituents of the oilseed crop ricinus communis and their pharmacological activities: a review.

Ricinus communis L. agronomic importance has stimulated a diverse set of studies related to pharmacological activities of extracts and compounds isolated from this plant. Phytochemical studies have shown that this species possesses a wide diversity of chemical compounds that presents relevant...

Author(s) : Ribeiro, P. R.; Castro, R. D. de; Fernandez, L. G.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Industrial Crops and Products 2016 Vol.91 pp.358-376

22. Effects of low dose ibogaine on subjective mood state and psychological performance.

Ethnopharmacological relevance: Root bark from Tabernanthe iboga has been used traditionally in West Africa as a psychoactive substance in religious rituals. In smaller doses it is reported anecdotally to have stimulant properties. Aim of the study: To evaluate the influence of a single 20 mg...

Author(s) : Forsyth, B.; Machado, L.; Jowett, T.; Jakobi, H.; Garbe, K.; Winter, H.; Glue, P.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.189 pp.10-13

23. Physicochemical evaluation and pharmacognostical standardization of Pellionia heyneana Wedd. leaf.

Introduction: Pellionia heyneana Wedd. Leaves have long been employed as a traditional remedy by the Cholanaikan tribe of South India to treat various ailments. Methods: Pharmacological and physicochemical evaluation of P. heyneana leaf has been carried out to determine its macro and microscopic...

Author(s) : Vilash, V.; Suja, S. R.; Latha, P. G.; Kumar, A. L. A.; Ragesh, R. N.; Rajasekharan, S.

Publisher : Phcog.Net, Bangalore, India

Journal article : Pharmacognosy Journal 2016 Vol.8 No.6 pp.551-556 ref.17

24. Kai-Xin-San, a traditional Chinese medicine formula, induces neuronal differentiation of cultured PC12 cells: modulating neurotransmitter regulation enzymes and potentiating NGF inducing neurite outgrowth.

Ethnopharmacological relevance: Kai-Xin-San, an ancient formula composed of Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma and Poria, was frequently applied for major depression disorders for thousands of years. However, its molecular mechanism has not clearly been...

Author(s) : Zhu Yue; Duan XiuZhu; Huang FeiYu; Cheng XiaoNan; Zhang Liu; Liu Pei; Shu-Lan Su; Duan JinAo; Dong TingXia [Dong, T. X. T. ]; Tsim WahKeung [Tsim, W. K. K. ]

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.193 pp.272-282

25. The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model.

Ethnopharmacological relevance: Sceletium tortuosum (L.) N.E. Br. has been reported to elevate mood, reduce anxiety and stress and alleviate pain. Aim of study This study sought to examine the effects of an S. tortuosum alkaloid enriched fraction in the chick anxiety-depression model, a model that...

Author(s) : Carpenter, J. M.; Jourdan, M. K.; Fountain, E. M.; Ali, Z.; Abe, N.; Khan, I. A.; Sufka, K. J.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.193 pp.329-332


Clinical pharmacology of Citrus bergamia: a systematic review. Citrus bergamia Risso et Poiteau ("Bergamot") originated from the Mediterranean ecoregion (southern Italy, Calabria). Bergamot essential oil (BEO) is used in perfumes, cosmetics, and for stress reduction. Juice from C. bergamia has been used for hyperlipidemia. We evaluated literature published on ...

Author(s) : Mannucci, C.; Navarra, M.; Calapai, F.; Squeri, R.; Gangemi, S.; Calapai, G.

Publisher : Wiley, Chichester, UK

Journal article : Phytotherapy Research 2017 Vol.31 No.1 pp.27-39 ref.47

15. Characterization of ion channels on subesophageal ganglion neurons from Chinese tarantula Ornithoctonus huwena: exploring the myth of the spider insensitive to its venom.

Chinese tarantula Ornithoctonus huwena is one of the most venomous spiders distributing in the hilly areas of southern China. In this study, using whole-cell patch-clamp technique we investigated electrophysiological and pharmacological properties of ion channels from tarantula subesophageal...

Author(s) : Deng MeiChun; Hu ZhaoTun; Cai TianFu; Liu Kai; Wu WenFang; Luo Xuan; Jiang LiPing; Wang MeiChi; Yang Jing; Xiao YuCheng; Liang SongPing

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Toxicon 2016 Vol.120 pp.61-68 ref.28

16. Description of Loxtox protein family and identification of a new group of Phospholipases D from Loxosceles similis venom gland.

Envenoming resulting from Loxosceles spider bites (loxoscelism) is a recognized public health problem in Brazil. However, the pathophysiology of loxoscelism caused by L. similis bites, which is widespread in Brazil, remains poorly understood. In the present work, the RNA sequencing (RNA-Seq - Next...

Author(s) : Dantas, A. E.; Carmo, A. O.; Horta, C. C. R.; Leal, H. G.; Oliveira-Mendes, B. B. R.; Martins, A. P. V.; Chávez-Olórtegui, C.; Kalapothakis, E.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Toxicon 2016 Vol.120 pp.97-106 ref.many

17. Untargeted MS-based small metabolite identification from the plant leaves and stems of Impatiens balsamina.

The identification of plant metabolites is very important for the understanding of plant physiology including plant growth, development and defense mechanism, particularly for herbal medicinal plants. The metabolite profile could possibly be used for future drug discovery since the pharmacological...

Author(s) : Chua LeeSuan

Publisher : Elsevier Masson, Paris, France

Journal article : Plant Physiology and Biochemistry 2016 Vol.106 pp.16-22 ref.48

18. Medicinal plant transcriptomes: the new gateways for accelerated understanding of plant secondary metabolism.

Medicinal plants are the vital source of numerous structurally diverse pharmacologically active metabolites collectively called as secondary metabolites finding extensive applications in traditional systems of medicine and in pharmaceutical industries. Several distinctive and complex pathways...

Author(s) : Sandhya Tripathi; Jadaun, J. S.; Muktesh Chandra; Sangwan, N. S.

Publisher : Cambridge University Press, Cambridge, UK

Journal article : Plant Genetic Resources: Characterization and Utilization 2016 Vol.14 No.4 pp.256-269 ref.96

19. Comparative powder microscopic and HPTLC studies on stem barks of Symplocos racemosa Roxb. and Symplocos crataegoides Ham.

Introduction: Comparative powder microscopic and HPTLC studies were carried out on stem barks of Symplocos racemosa Roxb. and Symplocos crataegoides Ham. to differentiate its identity in Ayurvedic formulations. Method: Powder microscopic and HPTLC studies of these barks were undertaken on a...

Author(s) : Nartunai Govindarajan; Cheekala, U. M. R.; Shantha Arcot; Susikumar Sundaramoorthy; Murugammal Shanmugam; Ramasamy Duraisamy; Cheemalapati, V. N.; Ilavarasan Raju

Publisher : Phcog.Net, Bangalore, India

Journal article : Pharmacognosy Journal 2016 Vol.8 No.4 pp.346-351 ref.14

20. Chemical and medico biological applications of the genus Costus (Gingers).

Many herbal remedies individually or in combination have been recommended in various medical treatises for the cure of different diseases. Medicinal plants have served as nature's gift to make disease free healthy life. The genus Costus Linn. Belongs to family Costaceae, which has been separated...

Author(s) : Anusha Ajayakumar; Sini, K. R.; Sreekanth, M. C.

Publisher : Journal of Chemical and Pharmaceutical Research, Jaipur, India

Journal article : Journal of Chemical and Pharmaceutical Research 2016 Vol.8 No.8 pp.453-458 ref.73

21. Chemical constituents of the oilseed crop ricinus communis and their pharmacological activities: a review.

Ricinus communis L. agronomic importance has stimulated a diverse set of studies related to pharmacological activities of extracts and compounds isolated from this plant. Phytochemical studies have shown that this species possesses a wide diversity of chemical compounds that presents relevant...

Author(s) : Ribeiro, P. R.; Castro, R. D. de; Fernandez, L. G.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Industrial Crops and Products 2016 Vol.91 pp.358-376

22. Effects of low dose ibogaine on subjective mood state and psychological performance.

Ethnopharmacological relevance: Root bark from Tabernanthe iboga has been used traditionally in West Africa as a psychoactive substance in religious rituals. In smaller doses it is reported anecdotally to have stimulant properties. Aim of the study: To evaluate the influence of a single 20 mg...

Author(s) : Forsyth, B.; Machado, L.; Jowett, T.; Jakobi, H.; Garbe, K.; Winter, H.; Glue, P.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.189 pp.10-13

23. Physicochemical evaluation and pharmacognostical standardization of Pellionia heyneana Wedd. leaf.

Introduction: Pellionia heyneana Wedd. Leaves have long been employed as a traditional remedy by the Cholanaikan tribe of South India to treat various ailments. Methods: Pharmacological and physicochemical evaluation of P. heyneana leaf has been carried out to determine its macro and microscopic...

Author(s) : Vilash, V.; Suja, S. R.; Latha, P. G.; Kumar, A. L. A.; Ragesh, R. N.; Rajasekharan, S.

Publisher : Phcog.Net, Bangalore, India

Journal article : Pharmacognosy Journal 2016 Vol.8 No.6 pp.551-556 ref.17

24. Kai-Xin-San, a traditional Chinese medicine formula, induces neuronal differentiation of cultured PC12 cells: modulating neurotransmitter regulation enzymes and potentiating NGF inducing neurite outgrowth.

Ethnopharmacological relevance: Kai-Xin-San, an ancient formula composed of Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma and Poria, was frequently applied for major depression disorders for thousands of years. However, its molecular mechanism has not clearly been...

Author(s) : Zhu Yue; Duan XiuZhu; Huang FeiYu; Cheng XiaoNan; Zhang Liu; Liu Pei; Shu-Lan Su; Duan JinAo; Dong TingXia [Dong, T. X. T. ]; Tsim WahKeung [Tsim, W. K. K. ]

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.193 pp.272-282

25. The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model.

Ethnopharmacological relevance: Sceletium tortuosum (L.) N.E. Br. has been reported to elevate mood, reduce anxiety and stress and alleviate pain. Aim of study This study sought to examine the effects of an S. tortuosum alkaloid enriched fraction in the chick anxiety-depression model, a model that...

Author(s) : Carpenter, J. M.; Jourdan, M. K.; Fountain, E. M.; Ali, Z.; Abe, N.; Khan, I. A.; Sufka, K. J.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Ethnopharmacology 2016 Vol.193 pp.329-332