Search results: 54,553 results (approx.)

1. Protective effects of crocin on testicular torsion/detorsion in rats.

Oxidative stress, caused by extreme accumulation of un-scavenged reactive oxygen species, plays an integral role in the Ischemia-Reperfusion (I/R) injury to the testicles following testicular torsion . The current research aimed to examine the protective effects of crocin as a natural antioxidant...

Author(s) : Ganjiani, V.; Ahmadi, N.; Divar, M. R.; Sharifiyazdi, H.; Meimandi-Parizi, A.

Publisher : Elsevier, New York, USA

Journal article : Theriogenology 2021 Vol.173 pp.241-248

2. Pure species discriminate against hybrids in the Drosophila melanogaster species subgroup.

Introgression, the exchange of alleles between species, is a common event in nature. This transfer of alleles between species must happen through fertile hybrids. Characterizing the traits that cause defects in hybrids illuminates how and when gene flow is expected to occur. Inviability and...

Author(s) : Serrato-Capuchina, A.; Schwochert, T. D.; Zhang, S.; Roy, B.; Peede, D.; Koppelman, C.; Matute, D. R.

Publisher : Wiley, Boston, USA

Journal article : Evolution : International Journal of Organic Evolution 2021 Vol.75 No.7 pp.1753-1774

3. Use of mice as experimental animals in laboratories that refer to the principles of animal welfare : a literature review.

Welfare of lab animals has two major problems, which are general maintenance and treatment technique during the experimental procedures. These problems are related to the researchers' treatment from the acceptance of the lab animals until the study is ended. Any researcher that uses laboratory...

Foreign Title :Kajian pustaka: penggunaan mencit sebagai hewan coba di laboratorium yang mengacu pada prinsip kesejahteraan hewan.

Author(s) : Mutiarahmi CitraNur; Hartady Tyagita; Lesmana Ronny

Publisher : Fakultas Kedokteran Hewan, Universitas Udayana, Denpasar, Indonesia

Journal article : Indonesia Medicus Veterinus 2021 Vol.10 No.1 pp.134-145 ref.37

4. Protective cranial implant caps for macaques.

Background: Neuroscience studies with macaque monkeys may require cranial implants to stabilize the head or gain access to the brain for scientific purposes. Wound management that promotes healing after the cranial implant surgery in non-human primates can be difficult as it is not necessarily...

Author(s) : Perry, B. A. L.; Mason, S.; Nacef, J.; Waddle, A.; Hynes, B.; Bergmann, C.; Schmid, M. C.; Petkov, C. I.; Thiele, A.; Mitchell, A. S.

Publisher : Elsevier Ltd, Oxford, UK

Journal article : Journal of Neuroscience Methods 2021 Vol.348 ref.13

5. A break from the pups: the effects of loft access on the welfare of lactating laboratory rats.

Rats (Rattus norvegicus) bred for research are typically confined with their litters until weaning, but will spend time away from pups when given the opportunity. We aimed to assess how dam welfare is affected by the ability to escape from their pups. Rat dams (n = 16) were housed in cages either...

Author(s) : Ratuski, A. S.; Weary, D. M.

Publisher : Public Library of Sciences (PLoS), San Francisco, USA

Journal article : PLoS ONE 2021 Vol.16 No.6 ref.35

6. Where is ethology heading? An invitation for collective metadisciplinary discussion.

Many factors can impact the advancement of scientific disciplines. In the study of animal behavior and cognition (i.e., Ethology), a lack of consensus about definitions or the emergence of some current events and inventions, among other aspects, may challenge the discipline's grounds within the...

Author(s) : Bueno-Guerra, N.

Publisher : MDPI AG, Basel, Switzerland

Journal article : Animals 2021 Vol.11 No.9 ref.103

7. Behavioral and reproductive effects of environmental enrichment and Pseudoloma neurophilia infection on adult zebrafish (Danio rerio).

Recent studies have shown beneficial effects of environmental enrichment (EE) for zebrafish, while infection of zebrafish with the common pathogen Pseudoloma neurophilia has negative effects. This study investigates the effects of P. neurophilia infection and EE in housing and breeding tanks on...

Author(s) : Estes, J. M.; Altemara, M. L.; Crim, M. J.; Fletcher, C. A.; Whitaker, J. W.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.249-258

8. Effects of daytime blue-enriched led light on physiologic parameters of three common mouse strains maintained on an IVC system.

Light has been a crucial part of everyday life since the beginning of time. Most recently, light-emitting diode (LED) light enriched in the blue-appearing portion of the visible spectrum (465 to 485 nm), which is more efficient in energy use, is becoming the normal lighting technology in facilities ...

Author(s) : Voros, G. B.; Dauchy, R. T.; Myers, L.; Hill, S. M.; Blask, D. E.; Dobek, G. L.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.259-271

9. Effects of laboratory housing conditions on core temperature and locomotor activity in mice.

Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific rigor and reproducibility. In these studies,...

Author(s) : Russell, L. N.; Hyatt, W. S.; Gannon, B. M.; Simecka, C. M.; Randolph, M. M.; Fantegrossi, W. E.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.272-280

10. Assessing accumulation of organic material on rodent cage accessories.

According to the 8th edition of the Guide for the Care and Use of Laboratory Animals (the Guide), rodent cage accessories, such as filter tops, should be sanitized at least once every 2 wk. We performed a study to test the hypothesis that organic contamination (measured by ATP content, expressed as ...

Author(s) : Allen, K. P.; Csida, T. J.; Thulin, J. D.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.281-288

11. Effects of oxygen supplementation on injectable and inhalant anesthesia in C57BL/6 mice.

Oxygen supplementation is rarely considered when anesthetizing laboratory mice, despite reports that mice become profoundly hypoxic under anesthesia. Little is known about the effects of hypoxia on anesthetic performance. This article focuses on the effects of oxygen supplementation on physiologic...

Author(s) : Blevins, C. E.; Celeste, N. A.; Marx, J. O.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.289-297

12. Evaluation of treatment options for ulcerative dermatitis in the P rat.

Rotational outbred adult rats, phenotypically selected to prefer drinking alcohol ("P" rats) frequently present with selfinflicted wounds and ulcerative dermatitis, similar to that seen in C57BL/6 mice. Historically, veterinary interventions used to address this clinical condition have included...

Author(s) : Skiles, B. A.; Boehm, C. A.; Peveler, J. L.; Hickman, D. L.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.311-318

13. Predictors of subcutaneous injection site reactions to sustained-release buprenorphine in rhesus macaques (Macaca mulatta).

Subcutaneous injection site reactions to sustained-release buprenorphine hydrochloride (Buprenorphine SR) in macaques have been reported in only a single case report. In the current study, we evaluated the incidence rate and predictors of buprenorphine SR reactions in the subcutaneous tissue of...

Author(s) : Haertel, A. J.; Schultz, M. A.; Colgin, L. M.; Johnson, A. L.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.329-336

14. Effects of three consecutive days of morphine or methadone administration on analgesia and open-field activity in mice with Ehrlich carcinoma.

This study assessed the exploratory behavioral responses in BALB/c mice inoculated with Ehrlich ascitic carcinoma after 3 consecutive days of treatment with morphine or methadone. Fifty-three female mice, 60 ± 10 d old, were used. Seven days after intraperitoneal tumor inoculation (2 × 106 cells),...

Author(s) : Rusch, E.; Bovi, M. F.; Martinelli, E. C.; Garcia-Gomes, M. S.; Mori, C. M.; Martins, D. S.; Carregaro, A. B.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.349-356

15. Effects of pair housing on patency of jugular catheters in rats (Rattus norvegicus).

Chronic vascular access devices are widely used in a variety of species for repeated blood sampling or substance administration. Jugular catheters are commonly used for studying addiction-related behaviors in rats. Rats with catheters have historically been individually housed for the duration of...

Author(s) : Krueger, L. D.; Chang, S. E.; Motoc, M.; Chojecki, M.; Freeman, Z. T.; Flagel, S. B.

Publisher : American Association for Laboratory Animal Science, Memphis, USA

Journal article : Journal of the American Association for Laboratory Animal Science 2021 Vol.60 No.3 pp.357-364

16. Hyperbaric oxygen therapy in wound healing in mice.

We investigated the local and systemic effects of hyperbaric oxygen therapy in BALB/C mice, exposed to two different exposure times, under 2.4 atmosphere (ATM). Fifteen animals were divided into three groups (GI, GII and Control) and underwent a surgical excision of a skin fragment of approximately ...

Author(s) : Amaral, B. P.; Krause, A.; Pasini, J. S.; Silva, Á. J. C.; Inkelmann, M. A.; Müller, D. C. M.

Publisher : FEPMVZ - Editora, Belo Horizonte, Brazil

Journal article : Arquivo Brasileiro de Medicina Veterinária e Zootecnia 2021 Vol.73 No.2 pp.361-366 ref.17

17. Biomechanical comparison of a notched head locking T-plate and a straight locking compression plate in a juxta-articular fracture model.

Objective: This investigation compared the biomechanical properties of a 2.0 mm locking compression notched head T-plate (NHTP) and 2.0 mm straight locking compression plate (LCP), in a simple transverse juxta-articular fracture model. Study Design: Two different screw configurations were compared...

Author(s) : Bird, G.; Glyde, M.; Hosgood, G.; Hayes, A.; Day, R.

Publisher : Georg Thieme Verlag KG, Stuttgart, Germany

Journal article : Veterinary and Comparative Orthopaedics and Traumatology 2021 Vol.34 No.3 pp.161-170 ref.45

18. Altered mRNA and protein expression of monocarboxylate transporter MCT1 in the cerebral cortex and cerebellum of prion protein knockout mice.

The effect of a cellular prion protein (PrPc) deficiency on neuroenergetics was primarily analyzed via surveying the expression of genes specifically involved in lactate/pyruvate metabolism, such as monocarboxylate transporters (MCT1, MCT2, MCT4). The aim of the present study was to elucidate a...

Author(s) : Ramljak, S.; Schmitz, M.; Repond, C.; Zerr, I.; Pellerin, L.

Publisher : MDPI AG, Basel, Switzerland

Journal article : International Journal of Molecular Sciences 2021 Vol.22 No.4 ref.37

19. Use of powdered mare's milk in the production of specialized sports nutrition products.

Based on the high nutritional and biological value of mare's milk, the uniqueness of its protein, fat, vitamin and mineral compositions, the article provides information on the chemical composition of dry mare's milk obtained by freeze-drying. On the basis of dry mare's milk, a recipe for sports...

Author(s) : Sarsembayev, Kh. S.; Sinyavskiy, Yu. A.; Ibraimov, Y. S.

Publisher : Al-Farabi Kazakh National University, Almaty, Kazakhstan

Journal article : Experimental Biology 2021 Vol.86 No.1 pp.78-87 ref.31

20. Monitoring and contamination incidence of gnotobiotic experiments performed in microisolator cages.

With the increased interest in the microbiome research, gnotobiotic animals and techniques emerged again as valuable tools to investigate functional effects of host-microbe and microbe-microbe interactions. The increased demand for gnotobiotic experiments has resulted in the greater need for...

Author(s) : Basic, M.; Bolsega, S.; Smoczek, A.; Gläsner, J.; Hiergeist, A.; Eberl, C.; Stecher, B.; Gessner, A.; Bleich, A.

Publisher : Elsevier GmbH, Munich, Germany

Journal article : International Journal of Medical Microbiology 2021 Vol.311 No.3 ref.35

21. Hemato-biochemical alterations and antioxidant status during drug-induced thyroid dysfunction in wister rats.

This study was carried to determine the effect of induced disturbance in thyroid hormones (hyperthyroidism and hypothyroidism in animal model). In this study, sixty adult male Wister strain rats (180-200 gm) were divided into four groups represented by two control groups for both drug-induced...

Author(s) : Elsaied, N.; Mokhbatly, A. A. A.; Farid, A. S.

Publisher : Faculty of Veterinary Medicine, Benha University, Toukh, Egypt

Journal article : Benha Veterinary Medical Journal 2021 Vol.40 No.1 pp.52-57 ref.39

22. Ameliorative effects of induced pluripotent stem cells on experimentally induced ovarian ablation in adult female rats.

The current study designed to evaluate the role of pluripotent stem cells (iPSc) on experimentally-induced ovarian ablation (OA) by evaluating of hematological parameters, FSH and E2 changes, molecular and histopathological examination. 50 female rats were divided into five groups with 10 in each...

Author(s) : Email, A. A. M. S.; Salem, N. I.; Azam, I. M.; Farid, A. S.

Publisher : Faculty of Veterinary Medicine, Benha University, Toukh, Egypt

Journal article : Benha Veterinary Medical Journal 2021 Vol.40 No.1 pp.47-51 ref.33

23. Shared and distinctive features of the gut microbiome of C57BL/6 mice from different vendors and production sites, and in response to a new vivarium.

Animal models play a critical role in establishing causal relationships between gut microbiota and disease. The laboratory mouse is widely used to study the role of microbes in various disorders; however, differences between mouse vendors, genetic lineages and husbandry protocols have been shown to ...

Author(s) : Long, L. L.; Svenson, K. L.; Mourino, A. J.; Michaud, M.; Fahey, J. R.; Waterman, L.; Vandegrift, K. L.; Adams, M. D.

Publisher : Nature America, Inc., New York, USA

Journal article : Lab Animal 2021 Vol.50 No.7 pp.185-195 ref.67

24. Special Issue: Regulated cell death.

This special issue opens with a broad overview on the current paradigms of nonaccidental cell death, covering the major aspects of some widely recognized and more recently characterized mechanisms of cell death, highlighting the recent advancements in the understanding and classification of these...

Publisher : Sage Publications, Thousand Oaks, USA

Journal issue : Veterinary Pathology 2021 Vol.58 No.4 pp.594-649

25. Restricted sensitivity of FJ-C staining to assess neuronal degeneration and death in preclinical mouse studies.

Fluorescein-derived fluorochromes and anionic dyes such as Fluoro-Jade (FJ) stains have been introduced to facilitate recognition of dying neurons in tissue sections. However, the definition of what is really detected by FJ-based stains and its sensitivity in the detection of neuronal cell death is ...

Author(s) : Santagostino, S. F.; Spinazzi, M.; Radaelli, E.

Publisher : Sage Publications, Thousand Oaks, USA

Journal article : Veterinary Pathology 2021 Vol.58 No.4 pp.643-649 ref.36